Here’s something Washington rarely talks about while it’s busy pushing more bureaucracy: sometimes less really is more—especially when it comes to medications for seniors. A new study suggests older adults discharged from hospitals while taking multiple prescriptions are less likely to regain independence during rehabilitation. Not exactly the “golden years” anyone signed up for.
The study, conducted in Japan and published Dec. 17 in BMC Geriatrics, examined the effects of polypharmacy—defined as taking six or more medications regularly—on elderly patients recovering in a convalescent rehabilitation hospital. Researchers analyzed data from 1,903 patients aged 65 and older who underwent rehab between April 2017 and March 2024.
Patients were recovering from one of three conditions: cerebrovascular disease, motor disorders affecting movement and muscle control, or disuse syndrome, which results from inactivity and leads to weakness and physical decline. Of the total group, a striking 62.1% were discharged while taking six or more medications, and more than 76% of those patients were 80 years old or older. That’s not exactly a small sample.
The study also found that patients on multiple medications were more likely to be taking benzodiazepine receptor agonists for anxiety or insomnia, along with laxatives and psychotropic medications commonly used for depression, anxiety, or psychosis. In other words, a lot of pills—and a lot of potential side effects.

Researchers discovered that patients with polypharmacy who were recovering from cerebrovascular disease or disuse syndrome scored significantly lower on the Functional Independence Measure, which evaluates how well a person can manage everyday activities after illness or injury. Interestingly, patients with motor disorders didn’t show the same association, proving that one-size-fits-all medicine rarely fits anyone particularly well.
The negative effects were strongest among patients over 80 and those recovering from stroke-related conditions or general weakness caused by inactivity. As one expert told Fox News Digital, even when medications serve a purpose, the body’s ability to tolerate and metabolize them declines with age—something common sense has been saying for years, even if policy makers haven’t been listening.
The takeaway is refreshingly straightforward: careful medication management matters. Reducing unnecessary prescriptions could help seniors recover better, regain independence, and actually enjoy life again. It’s a reminder that smart, patient-centered healthcare—focused on outcomes, not just checklists—is still possible. And with the right leadership prioritizing practical solutions, that kind of common-sense care can remain within reach.